Which of the following best represents the DSM-5-TR criteria for a Major Depressive Disorder episode?

• A. A single episode of sadness lasting two weeks.
• B. A minimum of five of nine symptoms during a two-week period, including either depressed mood or anhedonia, causing clinically significant distress or impairment, not attributable to substances or another medical condition.
• C. Seven symptoms for three weeks with impairment only.
• D. Four of eight symptoms for one week with distress or impairment.

Answer: (B)